[Oestrus suppression in a dairy herd by means of anti-GnRH vaccination Improvac®: A prospective field study].

Schmid, Robin Michael; Studer, Eveline; Hirsbrunner, Gabriela (2020). [Oestrus suppression in a dairy herd by means of anti-GnRH vaccination Improvac®: A prospective field study]. Schweizer Archiv für Tierheilkunde, 162(2), pp. 93-100. Gesellschaft Schweizer Tierärztinnen und Tierärzte 10.17236/sat00245

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INTRODUCTION The aim of this study was to evaluate the duration of estrus suppression after a double administration of the anti-GnRH vaccine Improvac® (Zoetis Schweiz GmbH, 2800 Delémont) in cows. Furthermore, it should be investigated, if a third administration could prolong the effect of the cycle suppression. A total of 21 cows (more than four weeks post partum) were vaccinated twice, at least 35 days apart, with 2 ml Improvac® (0.4 mg of a GnRH-analogon) subcutaneously on one side of the neck. Over a period of 368 days and in the course of 18 farm visits these cows were examined gynecologically and re-vaccinated if they showed signs of estrus behaviour or ovarian activity. After the second vaccination the cycle of the cows was suppressed for an average period of 114 days (59-175 days) and the effect could be prolonged by a booster of the vaccine for another 127 days in three cows. Estrus behaviour was absent for a longer period than ovarian activity was. The vaccine was tolerated well: apart from slight swelling at the injection site, no side effects were observed. Our results demonstrate that two immunizations with Improvac® are an easily applicable method for the suppression of cyclic activity in cows for a mean period of 114 days. The duration of cycle suppression was prolonged by a booster of the vaccination.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Clinic for Ruminants
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV)

UniBE Contributor:

Schmid, Robin Michael; Studer, Eveline and Hirsbrunner, Gabriela

Subjects:

600 Technology > 630 Agriculture
500 Science > 590 Animals (Zoology)
600 Technology > 610 Medicine & health

ISSN:

1664-2848

Publisher:

Gesellschaft Schweizer Tierärztinnen und Tierärzte

Language:

German

Submitter:

Nathalie Viviane Zollinger

Date Deposited:

14 Feb 2020 09:06

Last Modified:

11 Mar 2020 11:28

Publisher DOI:

10.17236/sat00245

PubMed ID:

32004139

Uncontrolled Keywords:

Anti-GnRH Brunst Immunisierung Improvac® Rind bovino cattle chaleurs estro immunisation immunizzazione oestrus vaches

BORIS DOI:

10.7892/boris.139916

URI:

https://boris.unibe.ch/id/eprint/139916

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