Acute kidney injury due to Leptospira interrogans in 4 foals and use of renal replacement therapy with intermittent hemodiafiltration in 1 foal.

Fouché, Nathalie; Graubner, Claudia; Lanz, Simone; Schweighauser, Ariane; Francey, Thierry; Gerber, Vinzenz (2020). Acute kidney injury due to Leptospira interrogans in 4 foals and use of renal replacement therapy with intermittent hemodiafiltration in 1 foal. Journal of veterinary internal medicine, 34(2), pp. 1007-1012. Wiley-Blackwell 10.1111/jvim.15713

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Four 2-month-old foals were presented to an equine hospital with acute kidney injury caused by Leptospira interrogans infection. Clinical signs were nonspecific and included lethargy, fever, and unwillingness to nurse. The most important hematologic and clinicopathologic findings were azotemia, anemia, thrombocytopenia, hyponatremia, and hypochloremia. The diagnosis was based on urinary real-time PCR, serology using a microscopic agglutination test, or both. The most important serovars involved were L. interrogans serogroup australis serovar Bratislava and Australis. Treatment consisted of IV fluid therapy and antimicrobial treatment. Renal replacement therapy with hemodiafiltration was performed in 1 of the foals. All foals survived to discharge. This report highlights the importance of early diagnosis and treatment in foals with acute kidney injury caused by L. interrogans infection.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Small Animal Clinic
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > Equine Clinic

UniBE Contributor:

Fouché, Nathalie Elisa; Graubner, Claudia; Lanz, Simone; Schweighauser, Ariane; Francey, Thierry and Gerber, Vinzenz

Subjects:

600 Technology > 630 Agriculture

ISSN:

0891-6640

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Ursula Therese Horst

Date Deposited:

14 Feb 2020 09:43

Last Modified:

28 Mar 2020 01:33

Publisher DOI:

10.1111/jvim.15713

PubMed ID:

31999382

Uncontrolled Keywords:

horse infection leptospirosis renal failure

BORIS DOI:

10.7892/boris.140323

URI:

https://boris.unibe.ch/id/eprint/140323

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