The Human Coronary Collateral Circulation, Its Extracardiac Anastomoses and Their Therapeutic Promotion.

Bigler, Marius Reto; Seiler, Christian (2019). The Human Coronary Collateral Circulation, Its Extracardiac Anastomoses and Their Therapeutic Promotion. International journal of molecular sciences, 20(15) Molecular Diversity Preservation International MDPI 10.3390/ijms20153726

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Cardiovascular disease remains the leading global cause of death, and the number of patients with coronary artery disease (CAD) and exhausted therapeutic options (i.e., percutaneous coronary intervention (PCI), coronary artery bypass grafting (CABG) and medical treatment) is on the rise. Therefore, the evaluation of new therapeutic approaches to offer an alternative treatment strategy for these patients is necessary. A promising research field is the promotion of the coronary collateral circulation, an arterio-arterial network able to prevent or reduce myocardial ischemia in CAD. This review summarizes the basic principles of the human coronary collateral circulation, its extracardiac anastomoses as well as the different therapeutic approaches, especially that of stimulating the extracardiac collateral circulation via permanent occlusion of the internal mammary arteries.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Bigler, Marius Reto and Seiler, Christian

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1661-6596

Publisher:

Molecular Diversity Preservation International MDPI

Language:

English

Submitter:

Andrea Stettler

Date Deposited:

02 Mar 2020 09:52

Last Modified:

02 Mar 2020 09:59

Publisher DOI:

10.3390/ijms20153726

PubMed ID:

31366096

Uncontrolled Keywords:

collateral artery growth in man collateral flow index extracardiac anastomoses human coronary collateral circulation permanent internal mammary artery occlusion

BORIS DOI:

10.7892/boris.141174

URI:

https://boris.unibe.ch/id/eprint/141174

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