Baumann, Frederic; Engelberger, Rolf Peter; Willenberg, Torsten Andreas; Do, Dai-Do; Kalka, Christoph; Baumgartner, Iris; Diehm, Nicolas Alexander (2013). Infrapopliteal lesion morphology in patients with critical limb ischemia: implications for the development of anti-restenosis technologies. Journal of endovascular therapy, 20(2), pp. 149-56. Phoenix, Ariz.: International Society of Endovascular Specialists 10.1583/1545-1550-20.2.149
Full text not available from this repository.Purpose : To angiographically evaluate infrapopliteal arterial lesion morphology in a consecutive series of patients presenting with critical limb ischemia (CLI) and undergoing infrapopliteal angioplasty. Methods : A prospective analysis was undertaken of a consecutive series of CLI patients undergoing endovascular therapy in a tertiary referral center in the year 2011. Morphological assessment of baseline angiograms obtained prior to revascularization included lesion length, assessment of calcification using a semi-quantitative scoring system, and reference vessel diameter (RVD) measurement. Delta RVDs were assessed subtracting distal RVDs from proximal RVDs. A total of 197 infrapopliteal lesions in 105 CLI patients (n=106 limbs) were assessed. Of these, 136 lesions were treated by endovascular means. Results : The average length of treated lesions was 87.1±43.8 mm in stenoses and 124.0±78.3 mm in chronic occlusions (p<0.001). Mean RVD proximal to the lesions was 1.88 mm whereas it was 1.66 mm distal to the lesions (p≤0.03). Mean arterial calcification was 1.15. Conclusion : This prospective angiographic series underlines the complex nature and extensive longitudinal involvement of infrapopliteal lesions in CLI patients. These findings should be taken into consideration for anti-restenosis concepts in this challenging subgroup of peripheral artery disease patients.
Item Type: |
Journal Article (Original Article) |
---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Angiology |
UniBE Contributor: |
Engelberger, Rolf Peter, Willenberg, Torsten Andreas, Do, Dai-Do, Baumgartner, Iris, Diehm, Nicolas Alexander |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1526-6028 |
Publisher: |
International Society of Endovascular Specialists |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:35 |
Last Modified: |
05 Dec 2022 14:11 |
Publisher DOI: |
10.1583/1545-1550-20.2.149 |
PubMed ID: |
23581754 |
Web of Science ID: |
000317996800004 |
URI: |
https://boris.unibe.ch/id/eprint/14138 (FactScience: 220975) |