Hypereosinophilia driven by GM-CSF in large-cell carcinoma of the lung

Lammel, Verena; Stoeckle, Christina; Padberg, Barbara; Zweifel, Roland; Kienle, Dirk L; Reinhart, Walter H; Simon, Hans-Uwe (2012). Hypereosinophilia driven by GM-CSF in large-cell carcinoma of the lung. Lung cancer, 76(3), pp. 493-5. Amsterdam: Elsevier 10.1016/j.lungcan.2012.02.014

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In contrast to leukocytosis, paraneoplastic hypereosinophilia is uncommon in lung cancer. We present a patient with large-cell carcinoma of the lung, in which cancer cells generate large amounts of GM-CSF leading to a leukemoid reaction with prominent hypereosinophilia and potentially involved in autocrine tumor stimulation.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Pharmacology

UniBE Contributor:

Merz, Christina, Simon, Hans-Uwe

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0169-5002

Publisher:

Elsevier

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:35

Last Modified:

05 Dec 2022 14:11

Publisher DOI:

10.1016/j.lungcan.2012.02.014

PubMed ID:

22420949

Web of Science ID:

000304688300036

URI:

https://boris.unibe.ch/id/eprint/14209 (FactScience: 221070)

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