[Early recognition and prevention of schizophrenia and other psychoses].

Meisenzahl, E.; Walger, P.; Schmidt, Stefanie Julia; Koutsouleris, N.; Schultze-Lutter, F. (2020). [Early recognition and prevention of schizophrenia and other psychoses]. Der Nervenarzt, 91(1), pp. 10-17. Springer 10.1007/s00115-019-00836-5

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The last two decades of clinical research have clearly demonstrated the comprehensive benefits of the early recognition and treatment of psychotic disorders. The attenuated and transient positive symptoms according to the ultrahigh risk criteria and the basic symptom criterion “Cognitive disturbances” are the main approaches for an indicated prevention. They have recently been recommended as criteria for a clinical high-risk (CHR) state of psychosis by the European Psychiatric Association (EPA) and, following these, in the German S3 guidelines for the treatment of schizophrenia by the German Association for Psychiatry, Psychotherapy and Psychosomatics (DGPPN); however, the efficacy of early treatment of patients with a CHR for psychoses critically depends on the development of prognostic instruments, which enable healthcare professionals to reliably identify these patients based on the individual objective risk profiles. An important goal is the treatment of functional deficits, which can be identified by an individual risk profile. The treatment of existing comorbid mental disorders, psychosocial problems and the prevention of potential future disorders also characterizes the recommendations of the EPA and DGPPN for early treatment, which favor psychotherapeutic, especially cognitive behavioral interventions over pharmacological treatment. The close interdisciplinary cross-sectoral cooperation between the disciplines of child and adolescent psychiatry, and adult psychiatry is of outstanding importance in this context.

Item Type:

Journal Article (Review Article)


07 Faculty of Human Sciences > Institute of Psychology > Clinical Psychology and Psychotherapy

UniBE Contributor:

Schmidt, Stefanie Julia


100 Philosophy > 150 Psychology
600 Technology > 610 Medicine & health






Melanie Best

Date Deposited:

26 Mar 2020 17:29

Last Modified:

30 Mar 2020 14:34

Publisher DOI:


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