Intractable coronary fibromuscular dysplasia leading to end‐stage heart failure and fatal heart transplantation

Cattaneo, Magdalena Maria; Moccetti, Marco; Cattaneo, Mattia; Sürder, Daniel; Suter, Thomas; Martinelli, Michele; Roost, Eva; Schmidli, Jürg; Banz, Yara; Schneiders, Carmen; Pedrazzini, Giovanni; Corti, Roberto; Räber, Lorenz; Crea, Filippo; Mohacsi, Paul; Gallino, Augusto (2020). Intractable coronary fibromuscular dysplasia leading to end‐stage heart failure and fatal heart transplantation. ESC Heart Failure, 7(2), pp. 714-720. Wiley 10.1002/ehf2.12626

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Coronary fibromuscular dysplasia is uncommon, and even rarer its unstable and recurrent course. We present the unique case of a 52-year-old woman who underwent in total 12 coronary angiographies and three percutaneous coronary intervention within 24 months because of repetitive acute coronary syndromes due to refractory spasm, dissection, restenosis all leading to end-stage heart failure, and heart transplantation. The patient died 12 days after the heart transplantation complicated by intraoperative acute thrombotic occlusion of left anterior descending artery of the graft despite normal pretransplant coronary angiography. Autopsy of the recipient heart confirmed coronary fibromuscular dysplasia with massive intimal hyperplasia and restenosis.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiovascular Surgery
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology
04 Faculty of Medicine > Service Sector > Institute of Pathology

UniBE Contributor:

Suter, Thomas; Martinelli, Michele; Roost, Eva; Schmidli, Jürg; Banz Wälti, Yara; Schneiders, Carmen Elisabeth; Räber, Lorenz and Mohacsi, Paul

Subjects:

600 Technology > 610 Medicine & health
500 Science > 570 Life sciences; biology

ISSN:

2055-5822

Publisher:

Wiley

Language:

English

Submitter:

Claudia Stalder

Date Deposited:

30 Apr 2020 11:49

Last Modified:

30 Apr 2020 11:49

Publisher DOI:

10.1002/ehf2.12626

PubMed ID:

31994838

BORIS DOI:

10.7892/boris.143454

URI:

https://boris.unibe.ch/id/eprint/143454

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