Intracranial Atherosclerotic Stenoses: Pathophysiology, Epidemiology, Risk Factors and Current Therapy Options.

Krasteva, Marina Petrova; Lau, Kui Kai; Mordasini, Pasquale; Tsang, Anderson Chun On; Heldner, Mirjam Rachel (2020). Intracranial Atherosclerotic Stenoses: Pathophysiology, Epidemiology, Risk Factors and Current Therapy Options. Advances in therapy, 37(5), pp. 1829-1865. Springer 10.1007/s12325-020-01291-4

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Intracranial atherosclerotic stenoses (ICAS) are one of the most common causes of first and recurrent cerebrovascular ischaemic events worldwide, with highest prevalence in Asian, Hispanic and African populations. Clinical trials have improved the understanding of epidemiology, risk factors and imaging characteristics of patients with ICAS. Current therapeutic approaches concerning these patients include management of risk factors, best medical therapy, potentially endovascular and rarely surgical therapy. In our review, we elucidate the current epidemiology and evidence in evaluation of risk factors and therapeutic options for providing favourable outcome for patients with ICAS.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology

UniBE Contributor:

Mordasini, Pasquale and Heldner, Mirjam Rachel

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0741-238X

Publisher:

Springer

Language:

English

Submitter:

Martin Zbinden

Date Deposited:

04 May 2020 11:55

Last Modified:

07 May 2020 01:33

Publisher DOI:

10.1007/s12325-020-01291-4

PubMed ID:

32270364

Uncontrolled Keywords:

Best medical therapy Endovascular therapy Intracranial atherosclerotic stenosis Surgical therapy

BORIS DOI:

10.7892/boris.143468

URI:

https://boris.unibe.ch/id/eprint/143468

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