Spider phobia is associated with decreased left amygdala volume: a cross-sectional study

Fisler, Melanie S; Federspiel, Andrea; Horn, Helge; Dierks, Thomas; Schmitt, Wolfgang; Wiest, Roland; de Quervain, Dominique J-F; Soravia, Leila M. (2013). Spider phobia is associated with decreased left amygdala volume: a cross-sectional study. BMC psychiatry, 13, p. 70. London: BioMed Central 10.1186/1471-244X-13-70

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Evidence from animal and human studies imply the amygdala as the most critical structure involved in processing of fear-relevant stimuli. In phobias, the amygdala seems to play a crucial role in the pathogenesis and maintenance of the disorder. However, the neuropathology of specific phobias remains poorly understood. In the present study, we investigated whether patients with spider phobia show altered amygdala volumes as compared to healthy control subjects.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Psychiatric Neurophysiology (discontinued)
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > UPD Murtenstrasse
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology

UniBE Contributor:

Fisler, Melanie; Federspiel, Andrea; Horn, Helge Joachim; Dierks, Thomas; Schmitt, Wolfgang; Wiest, Roland and Soravia, Leila

ISSN:

1471-244X

Publisher:

BioMed Central

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:36

Last Modified:

13 Dec 2014 17:08

Publisher DOI:

10.1186/1471-244X-13-70

PubMed ID:

23442196

Web of Science ID:

000315825300001

BORIS DOI:

10.7892/boris.14356

URI:

https://boris.unibe.ch/id/eprint/14356 (FactScience: 221307)

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