Protein immobilization technology for flow biocatalysis

Romero-Fernández, María; Paradisi, Francesca (2020). Protein immobilization technology for flow biocatalysis. Current opinion in chemical biology, 55, pp. 1-8. Elsevier 10.1016/j.cbpa.2019.11.008

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Enzymatic immobilization has been at the forefront of applied biocatalysis as it enables convenient isolation and reuse of the catalyst if the target reaction is conducted in batch, and it has opened up significant opportunities to conduct biocatalysis in continuous mode. Over the last few years, an array of techniques to immobilize enzymes have been developed, spanning from covalent multipoint attachment to noncovalent electrostatic strategies to rational architecture to suitably orient the enzyme(s). In addition, new materials have been adapted to support biological catalysts. Here, we discuss the advances of the last two years in enzyme immobilization for continuous flow applications.

Item Type:

Journal Article (Review Article)

Division/Institute:

08 Faculty of Science > Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP)

UniBE Contributor:

Paradisi, Francesca

Subjects:

500 Science > 570 Life sciences; biology
500 Science > 540 Chemistry

ISSN:

1367-5931

Publisher:

Elsevier

Language:

English

Submitter:

Francesca Paradisi

Date Deposited:

12 May 2020 15:39

Last Modified:

05 Dec 2022 15:38

Publisher DOI:

10.1016/j.cbpa.2019.11.008

BORIS DOI:

10.7892/boris.143791

URI:

https://boris.unibe.ch/id/eprint/143791

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