How many cancer patients use complementary and alternative medicine: a systematic review and metaanalysis

Horneber, Markus; Bueschel, Gerd; Dennert, Gabriele; Less, Danuta; Ritter, Erik; Zwahlen, Marcel (2012). How many cancer patients use complementary and alternative medicine: a systematic review and metaanalysis. Integrative cancer therapies, 11(3), pp. 187-203. Thousand Oaks, Calif.: Sage Publications 10.1177/1534735411423920

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Background. No comprehensive systematic review has been published since 1998 about the frequency with which cancer patients use complementary and alternative medicine (CAM). Methods. MEDLINE, AMED, and Embase databases were searched for surveys published until January 2009. Surveys conducted in Australia, Canada, Europe, New Zealand, and the United States with at least 100 adult cancer patients were included. Detailed information on methods and results was independently extracted by 2 reviewers. Methodological quality was assessed using a criteria list developed according to the STROBE guideline. Exploratory random effects metaanalysis and metaregression were applied. Results. Studies from 18 countries (152; >65 000 cancer patients) were included. Heterogeneity of CAM use was high and to some extent explained by differences in survey methods. The combined prevalence for “current use” of CAM across all studies was 40%. The highest was in the United States and the lowest in Italy and the Netherlands. Metaanalysis suggested an increase in CAM use from an estimated 25% in the 1970s and 1980s to more than 32% in the 1990s and to 49% after 2000. Conclusions. The overall prevalence of CAM use found was lower than often claimed. However, there was some evidence that the use has increased considerably over the past years. Therefore, the health care systems ought to implement clear strategies of how to deal with this. To improve the validity and reporting of future surveys, the authors suggest criteria for methodological quality that should be fulfilled and reporting standards that should be required.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM)

UniBE Contributor:

Zwahlen, Marcel




Sage Publications




Factscience Import

Date Deposited:

04 Oct 2013 14:36

Last Modified:

26 Sep 2017 22:06

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URI: (FactScience: 221350)

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