Genomic release-recapture experiment in the wild reveals within-generation polygenic selection in stickleback fish

Laurentino, Telma G; Moser, Dario; Roesti, Marius; Ammann, Matthias; Frey, Anja; Ronco, Fabrizia; Kueng, Benjamin; Berner, Daniel (2020). Genomic release-recapture experiment in the wild reveals within-generation polygenic selection in stickleback fish. Nature Communications, 11(1), p. 1928. Springer Nature 10.1038/s41467-020-15657-3

Preview

Text Laurentino et al 2020 Nat Comm.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (1MB) | Preview

How rapidly natural selection sorts genome-wide standing genetic variation during adaptation remains largely unstudied experimentally. Here, we present a genomic release-recapture experiment using paired threespine stickleback fish populations adapted to selectively different lake and stream habitats. First, we use pooled whole-genome sequence data from the original populations to identify hundreds of candidate genome regions likely under divergent selection between these habitats. Next, we generate F2 hybrids from the same lake-stream population pair in the laboratory and release thousands of juveniles into a natural stream habitat. Comparing the individuals surviving one year of stream selection to a reference sample of F2 hybrids allows us to detect frequency shifts across the candidate regions toward the genetic variants typical of the stream population—an experimental outcome consistent with polygenic directional selection. Our study reveals that adaptation in nature can be detected as a genome-wide signal over just a single generation.

Interest & Impact

Downloads

111 since deposited on 28 May 2020
14 in the past 12 months

Citations

5 Citations in Web of Science ®
6 Citations in Scopus

Search

in Google Scholar™

Services

Actions (login required)

Edit item

Actions (login required)

Edit item