Genomic release-recapture experiment in the wild reveals within-generation polygenic selection in stickleback fish

Laurentino, Telma G; Moser, Dario; Roesti, Marius; Ammann, Matthias; Frey, Anja; Ronco, Fabrizia; Kueng, Benjamin; Berner, Daniel (2020). Genomic release-recapture experiment in the wild reveals within-generation polygenic selection in stickleback fish. Nature Communications, 11(1), p. 1928. Springer Nature 10.1038/s41467-020-15657-3

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How rapidly natural selection sorts genome-wide standing genetic variation during adaptation remains largely unstudied experimentally. Here, we present a genomic release-recapture experiment using paired threespine stickleback fish populations adapted to selectively different lake and stream habitats. First, we use pooled whole-genome sequence data from the original populations to identify hundreds of candidate genome regions likely under divergent selection between these habitats. Next, we generate F2 hybrids from the same lake-stream population pair in the laboratory and release thousands of juveniles into a natural stream habitat. Comparing the individuals surviving one year of stream selection to a reference sample of F2 hybrids allows us to detect frequency shifts across the candidate regions toward the genetic variants typical of the stream population—an experimental outcome consistent with polygenic directional selection. Our study reveals that adaptation in nature can be detected as a genome-wide signal over just a single generation.

Item Type:

Journal Article (Original Article)

Division/Institute:

08 Faculty of Science > Department of Biology > Institute of Ecology and Evolution (IEE) > Evolutionary Ecology
08 Faculty of Science > Department of Biology > Institute of Ecology and Evolution (IEE)

UniBE Contributor:

Rösti, Marius Samuel

Subjects:

500 Science > 570 Life sciences; biology

ISSN:

2041-1723

Publisher:

Springer Nature

Language:

English

Submitter:

Catherine Peichel

Date Deposited:

28 May 2020 11:37

Last Modified:

31 May 2020 02:45

Publisher DOI:

10.1038/s41467-020-15657-3

PubMed ID:

32317640

BORIS DOI:

10.7892/boris.143865

URI:

https://boris.unibe.ch/id/eprint/143865

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