The Infantile Hemangioma Referral Score: A Validated Tool for Physicians.

Léauté-Labrèze, Christine; Baselga Torres, Eulalia; Weibel, Lisa; Boon, Laurence M; El Hachem, Maya; van der Vleuten, Catharina; Roessler, Jochen; Troilius Rubin, Agneta (2020). The Infantile Hemangioma Referral Score: A Validated Tool for Physicians. Pediatrics, 145(4) American Academy of Pediatrics 10.1542/peds.2019-1628

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OBJECTIVES Infantile hemangiomas (IHs) are common; some cases require timely referral and treatment to prevent complications. We developed and validated a reliable instrument for timely and adequate referral of patients with IH to experts by nonexpert primary physicians. METHODS In this multicenter, cross-sectional, observational study, we used a 3-stage process: (1) development of the Infantile Hemangioma Referral Score (IHReS) tool by IH experts who selected a representative set of 42 IH cases comprising images and a short clinical history, (2) definition of the gold standard for the 42 cases by a second independent committee of IH experts, and (3) IHReS validation by nonexpert primary physicians using the 42 gold standard cases. RESULTS A total of 60 primary physicians from 7 different countries evaluated the 42 gold standard cases (without reference to the IHReS tool); 45 primary physicians evaluated these cases using the IHReS questionnaire, and 44 completed retesting using the instrument. IHReS had a sensitivity of 96.9% (95% confidence interval 96.1%-97.8%) and a specificity of 55.0% (95% confidence interval 51.0%-59.0%). The positive predictive value and negative predictive value were 40.5% and 98.3%, respectively. Validation by experts and primary physicians revealed substantial agreement for interrater reliability and intrarater repeatability. CONCLUSIONS IHReS, a 2-part algorithm with a total of 12 questions, is an easy-to-use tool for primary physicians for the purpose of facilitating correct and timely referral of patients with IH. IHReS may help practitioners in their decision to refer patients to expert centers.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine > Paediatric Haematology/Oncology

UniBE Contributor:

Rössler, Jochen Karl

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0031-4005

Publisher:

American Academy of Pediatrics

Language:

English

Submitter:

Prof. Dr. Jochen Karl Rössler

Date Deposited:

20 May 2020 15:35

Last Modified:

20 May 2020 15:36

Publisher DOI:

10.1542/peds.2019-1628

PubMed ID:

32161112

BORIS DOI:

10.7892/boris.144045

URI:

https://boris.unibe.ch/id/eprint/144045

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