Zimmermann, Jakob; Macpherson, Andrew J. (2020). Breast Milk Modulates Transgenerational Immune Inheritance. Cell, 181(6), pp. 1202-1204. Cell Press 10.1016/j.cell.2020.05.030
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ROR-γt+ regulatory T cells (Tregs) of the colon can prevent excessive inflammation but also delay pathogen clearance. How these cells are regulated has remained elusive. In this issue of Cell, Ramanan et al. find that the set-point for ROR-γt+ Tregs is non-genetically maternally inherited during a critical time window after birth through immunoglobulin A present in breast milk.
Item Type: |
Journal Article (Further Contribution) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Gastroenterology 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Gastroenterologie / Mukosale Immunologie 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Gastroenterologie / Mukosale Immunologie |
UniBE Contributor: |
Zimmermann, Jakob, Macpherson, Andrew |
ISSN: |
0092-8674 |
Publisher: |
Cell Press |
Language: |
English |
Submitter: |
Professor Andrew Macpherson |
Date Deposited: |
24 Jun 2020 10:19 |
Last Modified: |
05 Dec 2022 15:39 |
Publisher DOI: |
10.1016/j.cell.2020.05.030 |
PubMed ID: |
32497500 |
BORIS DOI: |
10.7892/boris.144821 |
URI: |
https://boris.unibe.ch/id/eprint/144821 |
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