Breast Milk Modulates Transgenerational Immune Inheritance.

Zimmermann, Jakob; Macpherson, Andrew J. (2020). Breast Milk Modulates Transgenerational Immune Inheritance. Cell, 181(6), pp. 1202-1204. Cell Press 10.1016/j.cell.2020.05.030

[img] Text
1-s2.0-S0092867420306255-main.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (723kB)

ROR-γt+ regulatory T cells (Tregs) of the colon can prevent excessive inflammation but also delay pathogen clearance. How these cells are regulated has remained elusive. In this issue of Cell, Ramanan et al. find that the set-point for ROR-γt+ Tregs is non-genetically maternally inherited during a critical time window after birth through immunoglobulin A present in breast milk.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Gastroenterology
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Gastroenterologie / Mukosale Immunologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Gastroenterologie / Mukosale Immunologie

UniBE Contributor:

Zimmermann, Jakob, Macpherson, Andrew

ISSN:

0092-8674

Publisher:

Cell Press

Language:

English

Submitter:

Professor Andrew Macpherson

Date Deposited:

24 Jun 2020 10:19

Last Modified:

05 Dec 2022 15:39

Publisher DOI:

10.1016/j.cell.2020.05.030

PubMed ID:

32497500

BORIS DOI:

10.7892/boris.144821

URI:

https://boris.unibe.ch/id/eprint/144821

Actions (login required)

Edit item Edit item
Provide Feedback