Patterns of practice for adaptive and real-time radiation therapy (POP-ART RT) part II: offline and online plan adaption for interfractional changes.

Bertholet, Jenny; Anastasi, Gail; Noble, David; Bel, Arjan; van Leeuwen, Ruud; Roggen, Toon; Duchateau, Michael; Pilskog, Sara; Garibaldi, Cristina; Tilly, Nina; García-Mollá, Rafael; Bonaque, Jorge; Oelfke, Uwe; Aznar, Marianne C; Heijmen, Ben (2020). Patterns of practice for adaptive and real-time radiation therapy (POP-ART RT) part II: offline and online plan adaption for interfractional changes. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 153, pp. 88-96. Elsevier Scientific Publ. Ireland 10.1016/j.radonc.2020.06.017

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PURPOSE

The POP-ART RT study aims to determine to what extent and how intrafractional real-time respiratory motion management (RRMM), and plan adaptation for interfractional anatomical changes (ART) are used in clinical practice and to understand barriers to implementation. Here we report on part II: ART using more than one plan per target per treatment course.

MATERIALS AND METHODS

A questionnaire on the current practice of ART, wishes for expansion or implementation, and barriers to implementation was distributed worldwide. Four types of ART were discriminated: daily online replanning, online plan library, protocolled offline replanning (all three based on a protocol), and ad-hoc offline replanning.

RESULTS

The questionnaire was completed by 177 centres from 40 countries. ART was used by 61% of respondents (31% with protocol) for a median (range) of 3 (1-8) tumour sites. CBCT/MVCT was the main imaging modality except for online daily replanning (11 users) where 10 users used MR. Two thirds of respondents wished to implement ART for a new tumour site; 40% of these had plans to do it in the next 2 years. Human/material resources and technical limitations were the main barriers to further use and implementation.

CONCLUSIONS

ART was used for a broad range of tumour sites, mainly with ad-hoc offline replanning and for a median of 3 tumour sites. There was a large interest in implementing ART for more tumour sites, mainly limited by human/material resources and technical limitations. Daily online replanning was primarily performed on MR-linacs.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology

UniBE Contributor:

Bertholet, Jenny

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1879-0887

Publisher:

Elsevier Scientific Publ. Ireland

Language:

English

Submitter:

Beatrice Scheidegger

Date Deposited:

06 Jul 2020 17:16

Last Modified:

22 Dec 2020 01:31

Publisher DOI:

10.1016/j.radonc.2020.06.017

PubMed ID:

32579998

Uncontrolled Keywords:

Adaptive radiotherapy Image-guided radiotherapy (IGRT) Interfractional motion MR-guided radiotherapy Plan library Plan of the day Replanning

BORIS DOI:

10.7892/boris.144917

URI:

https://boris.unibe.ch/id/eprint/144917

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