Functional muscle strength recovery from nail gun injury to the primary motor cortex.

Andereggen, Lukas; Widmer, Hans Rudolf; Di Santo, Stefano; Andres, Robert Hans (2020). Functional muscle strength recovery from nail gun injury to the primary motor cortex. Regenerative medicine, 15(5), pp. 1603-1609. Future Medicine 10.2217/rme-2019-0146

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Aim: Functional recovery following injury to the primary motor cortex is an uncommon phenomenon, given the limited ability of neurons of the adult central nervous system to regenerate. Case description: We report on a patient with near complete functional muscle strength recovery from a marked monoparesis due to nail gun injury to the medial primary motor cortex. Besides surgical decision-making, we discuss possible related mechanisms and current challenges in the regenerative processes responsible for the functional recovery. Discussion: To achieve a favorable outcome, surgical decision-making to prevent secondary damage is of upmost importance. Lesion-induced inflammatory response may potentiate endogenous neurogenesis and neuronal plasticity and potentially contribute to the regenerative process involved.

Item Type:

Journal Article (Further Contribution)


04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurosurgery

UniBE Contributor:

Widmer, Hans Rudolf, Di Santo, Stefano


600 Technology > 610 Medicine & health




Future Medicine




Nicole Söll

Date Deposited:

07 Jul 2020 16:19

Last Modified:

05 Dec 2022 15:39

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

nail injury primary motor cortex regeneration secondary brain damage


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