Stereotactic Radiotherapy for the Management of Refractory Ventricular Tachycardia: Promise and Future Directions.

Jumeau, Raphael; Ozsahin, Mahmut; Schwitter, Juerg; Eliçin, Olgun; Reichlin, Tobias; Roten, Laurent; Andratschke, Nicolaus; Mayinger, Michael; Saguner, Ardan M; Steffel, Jan; Blanck, Oliver; Vozenin, Marie-Catherine; Moeckli, Raphael; Zeverino, Michele; Vallet, Véronique; Herrera-Siklody, Claudia; Pascale, Patrizio; Bourhis, Jean; Pruvot, Etienne (2020). Stereotactic Radiotherapy for the Management of Refractory Ventricular Tachycardia: Promise and Future Directions. Frontiers in cardiovascular medicine, 7(108), p. 108. Frontiers 10.3389/fcvm.2020.00108

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Ventricular tachycardia (VT) caused by myocardial scaring bears a significant risk of mortality and morbidity. Antiarrhythmic drug therapy (AAD) and catheter ablation remain the cornerstone of VT management, but both treatments have limited efficacy and potential adverse effects. Stereotactic body radiotherapy (SBRT) is routinely used in oncology to treat non-invasively solid tumors with high precision and efficacy. Recently, this technology has been evaluated for the treatment of VT. This review presents the basic underlying principles, proof of concept, and main results of trials and case series that used SBRT for the treatment of VT refractory to AAD and catheter ablation.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Radiation Oncology

UniBE Contributor:

Eliçin, Olgun; Reichlin, Tobias Roman and Roten, Laurent

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2297-055X

Publisher:

Frontiers

Language:

English

Submitter:

Beatrice Scheidegger

Date Deposited:

20 Jul 2020 11:01

Last Modified:

26 Jul 2020 02:49

Publisher DOI:

10.3389/fcvm.2020.00108

PubMed ID:

32671101

Uncontrolled Keywords:

ablation noninvasive radiotherapy stereotactic radiotherapy ventricular tachycardia

BORIS DOI:

10.7892/boris.145257

URI:

https://boris.unibe.ch/id/eprint/145257

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