Luedi, Markus M.; Schober, Patrick; Stauffer, Verena K.; Diekmann, Maja; Doll, Dietrich (2020). Global Gender Differences in Pilonidal Sinus Disease: A Random-Effects Meta-Analysis. World journal of surgery, 44(11), pp. 3702-3709. Springer-Verlag 10.1007/s00268-020-05702-z
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BACKGROUND
Pilonidal sinus disease (PSD) is traditionally associated with young male patients. While PSD is rare in Asia and Africa, lifestyles are changing considerably throughout the so-called developed world. We question that PSD is an overwhelmingly male disease and that the proportion of women suffering from PSD is worldwide evenly distributed in a homogenous matter.
METHODS
We analysed the world literature published between 1833 and 2018, expanding on the database created by Stauffer et al. Following correction for gender bias with elimination of men-only and women-only studies, data were processed using random-effects meta-analysis in the technique of DerSimonian and Laird.
RESULTS
The share of female pilonidal sinus disease patients analysed from all studies available in the world literature is 21%. There are marked regional differences including South America (39%), North America as well as Australia/New Zealand (29%) and Asia (7%), which are highly significant. These results stand fast even if analysis without gender bias corrections was applied.
CONCLUSION
The share of female patients suffering from PSD is considerable. It is time to think of PSD as a disease of both men and women. Previously unknown, there are significant regional differences worldwide; the reason(s) for the regional differences is still unclear.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic and Policlinic for Anaesthesiology and Pain Therapy |
UniBE Contributor: |
Lüdi, Markus |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0364-2313 |
Publisher: |
Springer-Verlag |
Language: |
English |
Submitter: |
Jeannie Wurz |
Date Deposited: |
05 Aug 2020 07:22 |
Last Modified: |
19 Jul 2024 00:25 |
Publisher DOI: |
10.1007/s00268-020-05702-z |
PubMed ID: |
32681319 |
BORIS DOI: |
10.7892/boris.145568 |
URI: |
https://boris.unibe.ch/id/eprint/145568 |
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