Bruggink, Robin; Baan, Frank; Kramer, Gem; Claessens, Colet; Kuijpers-Jagtman, Anne Marie; Bronkhorst, Ewald M.; Maal, Thomas J.J.; Ongkosuwito, Edwin (2020). The effect of lip closure on palatal growth in patients with unilateral clefts. PeerJ, 8(e9631), e9631. PeerJ, Ltd 10.7717/peerj.9631
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Objectives
The objective of this study was to compare maxillary dimensions and growth in newborns with Complete Unilateral Cleft Lip and Palate (UCLP) to healthy newborns before and after cheiloplasty. Additionally, a palatal growth curve is constructed to give more information about the natural growth before surgical intervention.
Methods
Twenty-eight newborns with complete UCLP were enrolled in this study. Multiple plaster-casts of each child during their first year were collected and grouped in before and after cheiloplasty. A previous developed semi-automatic segmentation tool was used to assess the maxillary dimensions and were compared to a healthy control group. Z-scores were calculated to indicate differences between the two populations and if cheiloplasty had influence on maxillary growth. Furthermore, the prediction model created in a previous study was used to indicate differences between predictions and the outcome in UCLP measurements. The analysis was tested for inter- and intra-observer variability.
Results
Results show differences in alveolar and palatal shape in UCLP patients in comparison with healthy controls. Prior to cheiloplasty an increased width and alveolar length was observed while the palatal depth was decreased. After cheiloplasty the widths moved towards normal but were still significantly larger.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > School of Dental Medicine > Department of Orthodontics |
UniBE Contributor: |
Kuijpers-Jagtman, Anne-Marie |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
2167-8359 |
Publisher: |
PeerJ, Ltd |
Language: |
English |
Submitter: |
Renate Imhof-Etter |
Date Deposited: |
18 Aug 2020 10:44 |
Last Modified: |
05 Dec 2022 15:40 |
Publisher DOI: |
10.7717/peerj.9631 |
BORIS DOI: |
10.7892/boris.145946 |
URI: |
https://boris.unibe.ch/id/eprint/145946 |
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