Nonverbal communication remains untouched: No beneficial effect of symptomatic improvement on poor gesture performance in schizophrenia.

Wüthrich, Florian; Pavlidou, Anastasia; Stegmayer, Katharina; Eisenhardt, Sarah; Moor, Jeanne; Schäppi, Lea; Vanbellingen, Tim; Bohlhalter, Stephan; Walther, Sebastian (2020). Nonverbal communication remains untouched: No beneficial effect of symptomatic improvement on poor gesture performance in schizophrenia. (In Press). Schizophrenia Research Elsevier 10.1016/j.schres.2020.08.013

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BACKGROUND

Gestures are an important part of communication. Patients with schizophrenia present gesture deficits that tend to deteriorate in the course of the disease and hamper functional outcome. This gesture deficit has been associated with motor abnormalities, cognitive impairment, and psychotic symptoms. Unaffected, first-degree relatives of schizophrenia patients share some subclinical motor and cognitive abnormalities. We aimed to investigate, whether gesture performance changes with symptomatic improvement in patients, and to test the longitudinal performance in unaffected, first-degree relatives.

METHODS

In this study, we measured gesture performance using a validated test in 33 patients, 29 first-degree relatives and 38 healthy controls. Measurements were completed shortly after admission and before discharge in patients. Performance was rated blindly by experts using video recordings of the gesture task. Additionally, we evaluated cognitive function and psychotic symptoms at both visits.

RESULTS

Gesture performance was poorer in relatives compared to controls and poorer in patients compared to both relatives and controls. Patients showed an improvement in psychopathology but a significant decrease in gesture performance at follow-up, while performance in the other groups remained stable. Proportional change of gesture performance correlated with change of cognitive function in patients, whereas there were no correlations with change of cognitive function in the other groups.

CONCLUSION

While symptom severity was reduced, the gesture deficit further deteriorated in schizophrenia. The finding argues for distinct processes contributing to poor nonverbal communication skills in patients, requiring novel alternative treatment efforts.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Translational Research Center
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Gerontechnology and Rehabilitation

UniBE Contributor:

Wüthrich, Florian; Pavlidou, Anastasia; Stegmayer, Katharina Deborah Lena; Eisenhardt, Sarah; Moor, Jeanne Yvonne; Schäppi, Lea; Vanbellingen, Tim; Bohlhalter, Stephan and Walther, Sebastian

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0920-9964

Publisher:

Elsevier

Funders:

[42] Schweizerischer Nationalfonds

Language:

English

Submitter:

Sebastian Walther

Date Deposited:

11 Sep 2020 13:48

Last Modified:

11 Sep 2020 13:53

Publisher DOI:

10.1016/j.schres.2020.08.013

PubMed ID:

32883557

Uncontrolled Keywords:

First-degree relatives Longitudinal Nonverbal communication Nonverbal skills Psychosis TULIA

BORIS DOI:

10.7892/boris.146368

URI:

https://boris.unibe.ch/id/eprint/146368

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