Mueller, F; Büchel, B; Köberle, D; Schürch, Stefan; Pfister, B; Krähenbühl, St; Fröhlich, Tanja; Largiader, C R; Joerger, M (2013). Gender-specific elimination of continuous-infusional 5-fluorouracil in patients with gastrointestinal malignancies: results from a prospective population pharmacokinetic study. Cancer chemotherapy and pharmacology, 71(2), pp. 361-70. Berlin: Springer 10.1007/s00280-012-2018-4
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Mueller2013_Article_Gender-specificEliminationOfCo.pdf - Published Version Available under License Publisher holds Copyright. Download (389kB) | Preview |
This study was initiated to assess the quantitative impact of patient anthropometrics and dihydropyrimidine dehydrogenase (DPYD) mutations on the pharmacokinetics (PK) of 5-fluorouracil (5FU) and to explore limited sampling strategies of 5FU.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Institute of Clinical Chemistry 08 Faculty of Science > Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP) |
UniBE Contributor: |
Büchel, Barbara, Schürch, Stefan, Fröhlich, Tanja, Largiadèr, Carlo Rodolfo |
Subjects: |
600 Technology > 610 Medicine & health 500 Science > 570 Life sciences; biology 500 Science > 540 Chemistry |
ISSN: |
0344-5704 |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:36 |
Last Modified: |
05 Dec 2022 14:11 |
Publisher DOI: |
10.1007/s00280-012-2018-4 |
PubMed ID: |
23139054 |
Web of Science ID: |
000314044200010 |
BORIS DOI: |
10.48350/14661 |
URI: |
https://boris.unibe.ch/id/eprint/14661 (FactScience: 221743) |
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