In vitro analysis of time-dependent red blood cell phase separation in a complex microchannel network

Mantegazza, Alberto; Clavica, Francesco; Obrist, Dominik (August 2020). In vitro analysis of time-dependent red blood cell phase separation in a complex microchannel network (Unpublished). In: XXV International Conference of Theoretical and Applied Mechanics. Milano, Italy. 23-28 August 2020.

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In this study we provided quantitative data on red blood cell (RBC) partitioning in 21 divergent bifurcations embedded in a complex in vitro network. In the majority of bifurcations the branch receiving a higher blood fraction received an even higher RBC fraction (classical partitioning). However, in some bifurcations the low-flow branch received a higher RBC flow fraction (reverse partitioning). Moreover, we found that the phase separation is strongly time dependent and some selected bifurcations oscillated between the two types of partitioning.

Item Type:

Conference or Workshop Item (Paper)

Division/Institute:

10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Cardiovascular Engineering (CVE)

Graduate School:

Graduate School for Cellular and Biomedical Sciences (GCB)

UniBE Contributor:

Mantegazza, Alberto; Clavica, Francesco and Obrist, Dominik

Subjects:

600 Technology > 620 Engineering

Funders:

[4] Swiss National Science Foundation

Language:

English

Submitter:

Alberto Mantegazza

Date Deposited:

06 Oct 2020 15:04

Last Modified:

06 Oct 2020 15:04

BORIS DOI:

10.7892/boris.146854

URI:

https://boris.unibe.ch/id/eprint/146854

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