The Evolving Role of the Clinical Microbiology Laboratory in Identifying Resistance in Gram-Negative Bacteria: An Update.

Endimiani, Andrea; Ramette, Alban; Rhoads, Daniel D.; Jacobs, Michael R. (2020). The Evolving Role of the Clinical Microbiology Laboratory in Identifying Resistance in Gram-Negative Bacteria: An Update. Infectious disease clinics of North America, 34(4), pp. 659-676. Elsevier 10.1016/j.idc.2020.08.001

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The evolution of resistance to antimicrobial agents in gram-negatives has challenged the role of the clinical microbiology laboratory to implement new methods for their timely detection. Recent development has enabled the use of novel methods for more rapid pathogen identification, antimicrobial susceptibility testing, and detection of resistance markers. Commonly used methods improve the rapidity of resistance detection from both cultured bacteria and specimens. This review focuses on the commercially available systems available together with their technical performance and possible clinical impact.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases > Research
04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases
04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases > Clinical Microbiology
04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases > General Bacteriology

UniBE Contributor:

Endimiani, Andrea and Ramette, Alban Nicolas

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health

ISSN:

1557-9824

Publisher:

Elsevier

Funders:

[4] Swiss National Science Foundation

Projects:

[1124] Whole Genome and Plasmid Sequencing for MDR Enterobacteriaceae Simultaneously Isolated from Multiple Human and Non-Human Settings: Deciphering Impact, Risks, and Dynamics for Resistance Transmission and Spread

Language:

English

Submitter:

Andrea Endimiani

Date Deposited:

07 Oct 2020 11:06

Last Modified:

11 Mar 2021 02:18

Publisher DOI:

10.1016/j.idc.2020.08.001

PubMed ID:

33011047

Uncontrolled Keywords:

AST Blood LAMP MALDI-TOF PCR Rapid Sequencing T2MR

BORIS DOI:

10.7892/boris.146873

URI:

https://boris.unibe.ch/id/eprint/146873

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