Network Meta-Analysis

Nikolakopoulou, Adriani; White, Ian R.; Salanti, Georgia (2020). Network Meta-Analysis. In: Handbook of Meta-Analysis (pp. 187-218). New York: Chapman and Hall/CRC 10.1201/9781315119403

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Network meta-analysis aims to compare multiple interventions by synthesizing studies where each study compares only some of the interventions. This chapter explains how direct and indirect evidence are synthesized to compare interventions linked in a network of trials under the assumptions of consistency and transitivity. It defines the statistical model used for network meta-analysis under consistency, using various perspectives and implementations to shed more light on the model, and describes various ways in which the model may be extended to explore inconsistency. It then shows how network meta-analysis results may be interpreted using tools to rank the interventions. Topics common to all meta-analysis work, such as meta-regression and publication bias, are discussed in the network meta-analysis case, and available software is described.

Item Type:

Book Section (Book Chapter)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM)

UniBE Contributor:

Nikolakopoulou, Adriani and Salanti, Georgia

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISBN:

9781315119403

Publisher:

Chapman and Hall/CRC

Language:

English

Submitter:

Doris Kopp Heim

Date Deposited:

16 Oct 2020 12:30

Last Modified:

01 Dec 2020 20:07

Publisher DOI:

10.1201/9781315119403

BORIS DOI:

10.7892/boris.147113

URI:

https://boris.unibe.ch/id/eprint/147113

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