Precision Medicine in the Diagnosis and Management of Orthopedic Biofilm Infections

Baldan, Rossella; Sendi, Parham (2020). Precision Medicine in the Diagnosis and Management of Orthopedic Biofilm Infections. Frontiers in medicine, 7, p. 580671. Frontiers 10.3389/fmed.2020.580671

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Orthopedic biofilm infections are difficult to treat and require a multidisciplinary approach to diagnostics and management. Recent advances in the field include methods to disrupt biofilm, sequencing tools, and antibiotic susceptibility tests for bacteria residing in biofilm. The observation of interclonal differences in biofilm properties of the causative microorganisms, together with considerations of comorbidities and polypharmacy in a growing aging population, calls for a personalized approach to treat these infections. In this article, we highlight aspects of precision medicine that may open new perspectives in the diagnosis and management of orthopedic biofilm infections.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases > Research
04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases

UniBE Contributor:

Baldan, Rossella and Sendi, Parham

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2296-858X

Publisher:

Frontiers

Language:

English

Submitter:

Parham Sendi

Date Deposited:

12 Nov 2020 12:19

Last Modified:

10 Jan 2021 02:49

Publisher DOI:

10.3389/fmed.2020.580671

PubMed ID:

33240905

BORIS DOI:

10.7892/boris.147273

URI:

https://boris.unibe.ch/id/eprint/147273

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