Effects of Alzheimer caregiving on allostatic load

Roepke, Susan K; Mausbach, Brent T; Patterson, Thomas L; Von Känel, Roland; Ancoli-Israel, Sonia; Harmell, Alexandrea L; Dimsdale, Joel E; Aschbacher, Kirstin; Mills, Paul J; Ziegler, Michael G; Allison, Matthew; Grant, Igor (2011). Effects of Alzheimer caregiving on allostatic load. Journal of health psychology, 16(1), pp. 58-69. London: Sage Publications 10.1177/1359105310369188

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This study aimed to determine if Alzheimer caregivers have increased allostatic load compared to non-caregivers. Potential psychological moderators (mastery, depression, and role overload) of the relationship between caregiving status and allostatic load were also explored. Eighty-seven caregivers and 43 non-caregivers underwent biological assessment of allostatic load and psychological assessments. Caregivers had significantly higher allostatic load compared to non-caregivers ( p < .05). Mastery, but not depression or overload, moderated the relationship between caregiving status and allostatic load. In conclusion, allostatic load may represent a link explaining how stress translates to downstream pathology, but more work is necessary to understand the role of psychological factors.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology > Centre of Competence for Psychosomatic Medicine

UniBE Contributor:

von Känel, Roland




Sage Publications




Factscience Import

Date Deposited:

04 Oct 2013 14:10

Last Modified:

04 May 2014 23:05

Publisher DOI:


PubMed ID:


Web of Science ID:



https://boris.unibe.ch/id/eprint/1474 (FactScience: 203144)

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