Vascular Events, Vascular Disease and Vascular Risk Factors-Strongly Intertwined with COVID-19.

Scutelnic, Adrian; Heldner, Mirjam R (2020). Vascular Events, Vascular Disease and Vascular Risk Factors-Strongly Intertwined with COVID-19. Current treatment options in neurology, 22(11), p. 40. Current Science Inc. 10.1007/s11940-020-00648-y

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Purpose of review

To elucidate the intertwining of vascular events, vascular disease and vascular risk factors and COVID-19.

Recent findings

Strokes are a leading cause of disability and death worldwide. Vascular risk factors are important drivers of strokes. There are unmodifiable vascular risk factors such as age and ethnicity and modifiable vascular risk factors. According to the INTERSTROKE study, the 10 most frequent modifiable vascular risk factors are arterial hypertension, physical inactivity, overweight, dyslipidaemia, smoking, unhealthy diet, cardiac pathologies, diabetes mellitus, stress/depression and overconsumption of alcohol. Also, infection and inflammation have been shown to increase the risk of stroke. There is high-quality evidence for the clinical benefits of optimal primary and secondary stroke prevention. The COVID-19 pandemic brought a new perspective to this field. Vascular events, vascular disease and vascular risk factors-and COVID-19-are strongly intertwined. An increased risk of vascular events-by multifactorial mechanisms-has been observed in COVID-19 patients. Also, a higher rate of infection with COVID-19, severe COVID-19 and bad outcome has been demonstrated in patients with pre-existing vascular disease and vascular risk factors.


At present, we suggest that regular interactions between healthcare professionals and patients should include education on COVID-19 and on primary and secondary vascular prevention in order to reduce the burden of disease in our ageing populations.

Item Type:

Journal Article (Review Article)


04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology

UniBE Contributor:

Scutelnic, Adrian and Heldner, Mirjam Rachel


600 Technology > 610 Medicine & health




Current Science Inc.




Chantal Kottler

Date Deposited:

27 Oct 2020 15:06

Last Modified:

17 Mar 2021 16:09

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

COVID-19 Ischaemic stroke Prevention Vascular events Vascular risk factors




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