Predictors of Outcomes Following Transcatheter Edge-to-Edge Mitral Valve Repair.

Ben-Shoshan, Jeremy; Overtchook, Pavel; Buithieu, Jean; Mousavi, Negar; Martucci, Giuseppe; Spaziano, Marco; de Varennes, Benoit; Lachapelle, Kevin; Brophy, James; Modine, Thomas; Baumbach, Andreas; Maisano, Francesco; Prendergast, Bernard; Tamburino, Corrado; Windecker, Stephan; Piazza, Nicolo (2020). Predictors of Outcomes Following Transcatheter Edge-to-Edge Mitral Valve Repair. JACC. Cardiovascular Interventions, 13(15), pp. 1733-1748. Elsevier 10.1016/j.jcin.2020.03.025

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Transcatheter edge-to-edge mitral valve repair is a viable alternative to surgery in patients with severe mitral regurgitation and high surgical risk. Yet the specific group of patients who would optimally benefit from this therapy remains to be determined. Selection of patients for transcatheter strategy is currently based on surgical prognostic scores and technical feasibility. Meanwhile, various clinical, anatomic, and procedural factors have been recently recognized as predictors of adverse outcomes following transcatheter edge-to-edge mitral valve repair, including device failure, recurrent mitral regurgitation, and mortality. Integration of these prognostic factors in the decision-making process of the heart team might improve patient management and outcomes. Herein, the authors review the different factors related to symptomatic status, comorbidity, serum biomarkers, echocardiographic findings, and procedural technique that have been identified as independent predictors of adverse outcome following transcatheter edge-to-edge mitral valve repair and discuss their potential application in everyday clinical practice.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Windecker, Stephan

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1876-7605

Publisher:

Elsevier

Language:

English

Submitter:

Nadia Biscozzo

Date Deposited:

18 Nov 2020 09:38

Last Modified:

18 Nov 2020 09:38

Publisher DOI:

10.1016/j.jcin.2020.03.025

PubMed ID:

32763070

Uncontrolled Keywords:

adverse outcomes mitral regurgitation predictors transcatheter edge-to-edge mitral valve repair

BORIS DOI:

10.7892/boris.147455

URI:

https://boris.unibe.ch/id/eprint/147455

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