The PASCAL Device-Early Experience with a Leaflet Approximation Device: What Are the Benefits/Limitations Compared with the MitraClip?

Corpataux, Noé; Winkel, Mirjam Gauri; Kassar, Mohammad; Brugger, Nicolas; Windecker, Stephan; Praz, Fabien (2020). The PASCAL Device-Early Experience with a Leaflet Approximation Device: What Are the Benefits/Limitations Compared with the MitraClip? Current cardiology reports, 22(8), p. 74. Springer 10.1007/s11886-020-01305-1

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PURPOSE OF REVIEW

This review article describes the technical features of the novel Edwards PASCAL transcatheter valve repair system as well as the evidence accumulated so far.

RECENT FINDINGS

Transcatheter mitral and tricuspid valve leaflet approximation enable treatment of patients with mitral and tricuspid regurgitation who are not eligible for surgery. The PASCAL device offers an alternative that may allow to overcome some of the limitations of previous systems and open the path for an approach adapted to individual patient's anatomy. Early data show similar safety and efficacy compared with the Abbott MitraClip system. The PASCAL system is a valuable addition to the armamentarium of transcatheter mitral and tricuspid valve repair devices. Randomized head-to-head comparisons and long-term data are needed to confirm the promising results observed so far.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Winkel, Mirjam Gauri; Kassar, Mohammad; Brugger, Nicolas Jacques; Windecker, Stephan and Praz, Fabien

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1523-3782

Publisher:

Springer

Language:

English

Submitter:

Nadia Biscozzo

Date Deposited:

25 Nov 2020 13:57

Last Modified:

25 Nov 2020 13:57

Publisher DOI:

10.1007/s11886-020-01305-1

PubMed ID:

32594261

Uncontrolled Keywords:

Edge-to-edge valve repair Leaflet approximation MitraClip Mitral regurgitation PASCAL Transcatheter mitral valve repair Transcatheter tricuspid valve repair Tricuspid regurgitation

BORIS DOI:

10.7892/boris.147468

URI:

https://boris.unibe.ch/id/eprint/147468

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