Corona Immunitas: study protocol of a nationwide program of SARS-CoV-2 seroprevalence and seroepidemiologic studies in Switzerland.

West, Erin A; Anker, Daniela; Amati, Rebecca; Richard, Aude; Wisniak, Ania; Butty, Audrey; Albanese, Emiliano; Bochud, Murielle; Chiolero, Arnaud; Crivelli, Luca; Cullati, Stéphane; d'Acremont, Valérie; Epure, Adina Mihaela; Fehr, Jan; Flahault, Antoine; Fornerod, Luc; Frank, Irène; Frei, Anja; Michel, Gisela; Gonseth, Semira; ... (2020). Corona Immunitas: study protocol of a nationwide program of SARS-CoV-2 seroprevalence and seroepidemiologic studies in Switzerland. International journal of public health, 65(9), pp. 1529-1548. SP Birkhäuser Verlag Basel 10.1007/s00038-020-01494-0

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OBJECTIVES

Seroprevalence studies to assess the spread of SARS-CoV-2 infection in the general population and subgroups are key for evaluating mitigation and vaccination policies and for understanding the spread of the disease both on the national level and for comparison with the international community.

METHODS

Corona Immunitas is a research program of coordinated, population-based, seroprevalence studies implemented by Swiss School of Public Health (SSPH+). Over 28,340 participants, randomly selected and age-stratified, with some regional specificities will be included. Additional studies in vulnerable and highly exposed subpopulations are also planned. The studies will assess population immunological status during the pandemic.

RESULTS

Phase one (first wave of pandemic) estimates from Geneva showed a steady increase in seroprevalence up to 10.8% (95% CI 8.2-13.9, n = 775) by May 9, 2020. Since June, Zurich, Lausanne, Basel City/Land, Ticino, and Fribourg recruited a total of 5973 participants for phase two thus far.

CONCLUSIONS

Corona Immunitas will generate reliable, comparable, and high-quality serological and epidemiological data with extensive coverage of Switzerland and of several subpopulations, informing health policies and decision making in both economic and societal sectors. ISRCTN Registry: https://www.isrctn.com/ISRCTN18181860 .

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine > Centre of Competence for General Internal Medicine
04 Faculty of Medicine > Medical Education > Institute of General Practice and Primary Care (BIHAM)

UniBE Contributor:

Chiolero, Arnaud and Rodondi, Nicolas

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

1661-8556

Publisher:

SP Birkhäuser Verlag Basel

Language:

English

Submitter:

Doris Kopp Heim

Date Deposited:

27 Oct 2020 20:51

Last Modified:

06 Jan 2021 12:36

Publisher DOI:

10.1007/s00038-020-01494-0

PubMed ID:

33098441

Uncontrolled Keywords:

Hygiene practices Longitudinal Prevalence SARS-CoV-2 Serosurvey Socioeconomic differences

BORIS DOI:

10.7892/boris.147576

URI:

https://boris.unibe.ch/id/eprint/147576

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