Achterhof, Alexandra B; Rozsnyai, Zsofia; Reeve, Emily; Jungo, Katharina Tabea; Floriani, Carmen; Poortvliet, Rosalinde K E; Rodondi, Nicolas; Gussekloo, Jacobijn; Streit, Sven (2020). Potentially inappropriate medication and attitudes of older adults towards deprescribing. PLoS ONE, 15(10), e0240463. Public Library of Science 10.1371/journal.pone.0240463
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INTRODUCTION
Multimorbidity and polypharmacy are current challenges when caring for the older population. Both have led to an increase of potentially inappropriate medication (PIM), illustrating the need to assess patients' attitudes towards deprescribing. We aimed to assess the prevalence of PIM use and whether this was associated with patient factors and willingness to deprescribe.
METHOD
We analysed data from the LESS Study, a cross-sectional study on self-reported medication and on barriers and enablers towards the willingness to deprescribe (rPATD questionnaire). The survey was conducted among multimorbid (≥3 chronic conditions) participants ≥70 years with polypharmacy (≥5 long-term medications). A subset of the Beers 2019 criteria was applied for the assessment of medication appropriateness.
RESULTS
Data from 300 patients were analysed. The mean age was 79.1 years (SD 5.7). 53% had at least one PIM (men: 47.8%%, women: 60.4%%; p = 0.007). A higher number of medications was associated with PIM use (p = 0.002). We found high willingness to deprescribe in both participants with and without PIM. Willingness to deprescribe was not associated with PIM use (p = 0.25), nor number of PIMs (p = 0.81).
CONCLUSION
The willingness of older adults with polypharmacy towards deprescribing was not associated with PIM use in this study. These results suggest that patients may not be aware if they are taking PIMs. This implies the need for raising patients' awareness about PIMs through education, especially in females, in order to implement deprescribing in daily practice.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Medical Education > Institute of General Practice and Primary Care (BIHAM) 04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine > Centre of Competence for General Internal Medicine |
Graduate School: |
Graduate School for Health Sciences (GHS) |
UniBE Contributor: |
Rozsnyai, Zsófia, Jungo, Katharina Tabea, Floriani, Carmen, Rodondi, Nicolas, Streit, Sven |
Subjects: |
600 Technology > 610 Medicine & health 300 Social sciences, sociology & anthropology > 360 Social problems & social services |
ISSN: |
1932-6203 |
Publisher: |
Public Library of Science |
Language: |
English |
Submitter: |
Doris Kopp Heim |
Date Deposited: |
27 Oct 2020 21:02 |
Last Modified: |
05 Dec 2022 15:41 |
Publisher DOI: |
10.1371/journal.pone.0240463 |
PubMed ID: |
33104695 |
BORIS DOI: |
10.7892/boris.147577 |
URI: |
https://boris.unibe.ch/id/eprint/147577 |
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