It Takes Two to Tango: DPRs in ALS and SCA36.

Maharjan, Niran; Saxena, Smita (2020). It Takes Two to Tango: DPRs in ALS and SCA36. Neuron, 107(2), pp. 202-204. Cell Press 10.1016/j.neuron.2020.06.025

[img] Text
Maharjan, 2020, It Takes Two to Tango.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (385kB) | Request a copy

Dipeptide repeat proteins (DPRs) occur via repeat-associated non-AUG (RAN) translation. In this issue of Neuron, McEachin et al. (2020) show that the aggregation-prone poly(GA)-rich chimeric DPRs determine divergent poly(GP) mediated pathology between C9ALS/FTD and SCA36.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DCR Unit Sahli Building > Forschungsgruppe Neurologie
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology

UniBE Contributor:

Maharjan, Niran and Saxena, Smita

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0896-6273

Publisher:

Cell Press

Language:

English

Submitter:

Chantal Kottler

Date Deposited:

13 Nov 2020 14:38

Last Modified:

13 Nov 2020 14:38

Publisher DOI:

10.1016/j.neuron.2020.06.025

PubMed ID:

32702342

BORIS DOI:

10.7892/boris.147714

URI:

https://boris.unibe.ch/id/eprint/147714

Actions (login required)

Edit item Edit item
Provide Feedback