Zika Virus.

Masmejan, Sophie; Musso, Didier; Vouga, Manon; Pomar, Leo; Dashraath, Pradip; Stojanov, Milos; Panchaud, Alice; Baud, David (2020). Zika Virus. Pathogens, 9(11), p. 898. MDPI AG 10.3390/pathogens9110898

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Zika virus (ZIKV), a neurotropic single-stranded RNA flavivirus, remains an important cause of congenital infection, fetal microcephaly, and Guillain-Barré syndrome in populations where ZIKV has adapted to a nexus involving the Aedes mosquitoes and humans. To date, outbreaks of ZIKV have occurred in Africa, Southeast Asia, the Pacific islands, the Americas, and the Caribbean. Emerging evidence, however, suggests that the virus also has the potential to cause infections in Europe, where autochtonous transmission of the virus has been identified. This review focuses on evolving ZIKV epidemiology, modes of transmission and host-virus interactions. The clinical manifestations, diagnostic issues relating to cross-reactivity to the dengue flavivirus and concerns surrounding ZIKV infection in pregnancy are discussed. In the last section, current challenges in treatment and prevention are outlined.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Medical Education > Institute of General Practice and Primary Care (BIHAM)

UniBE Contributor:

Panchaud Monnat, Alice Elke Martine

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

2076-0817

Publisher:

MDPI AG

Language:

English

Submitter:

Doris Kopp Heim

Date Deposited:

04 Nov 2020 11:34

Last Modified:

16 Dec 2020 19:34

Publisher DOI:

10.3390/pathogens9110898

PubMed ID:

33126413

Uncontrolled Keywords:

Guillain-Barré syndrome Zika Zika virus congenital Zika syndrome emerging infectious diseases materno-fetal infections

BORIS DOI:

10.7892/boris.147805

URI:

https://boris.unibe.ch/id/eprint/147805

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