[Pathogenesis of functional gastrointestinal disorders - an interdisciplinary perspective]

Egloff, N; Beer, C; Gschossmann, J M; Sendensky, A H; von Känel, R (2010). [Pathogenesis of functional gastrointestinal disorders - an interdisciplinary perspective]. Praxis - schweizerische Rundschau für Medizin, 99(7), pp. 419-27. Bern: Huber

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Functional gastrointestinal disorders (FGD) are highly prevalent worldwide. Recent research demonstrates that complex and interacting biological and behavioral mechanisms contribute particularly to the pathogenesis of irritable bowel syndrome and functional dyspepsia. Dysregulation of the enteral, neuroenteric, visceral-autonomic, and central nervous systems are important biological contributors, whereas the psychological state of a patient may evidently modulate aspects related to biological stress reactivity and somatic perception both playing a role in the clinical manifestation of FGD. Our overview clearly shows that an interdisciplinary perspective of the pathogenesis of FGD may best serve clinicians and patients.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology > Centre of Competence for Psychosomatic Medicine
04 Faculty of Medicine > Service Sector > Institute of Clinical Pharmacology and Visceral Research [discontinued]

UniBE Contributor:

Egloff, Niklaus, Beer, Christine Elisabeth, Sendensky, Alexander, von Känel, Roland








Factscience Import

Date Deposited:

04 Oct 2013 14:10

Last Modified:

05 Dec 2022 14:01

PubMed ID:



https://boris.unibe.ch/id/eprint/1479 (FactScience: 203149)

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