COVID-19: Mechanisms of Vaccination and Immunity.

Speiser, Daniel E.; Bachmann, Martin (2020). COVID-19: Mechanisms of Vaccination and Immunity. Vaccines, 8(3) MDPI 10.3390/vaccines8030404

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Vaccines are needed to protect from SARS-CoV-2, the virus causing COVID-19. Vaccines that induce large quantities of high affinity virus-neutralizing antibodies may optimally prevent infection and avoid unfavorable effects. Vaccination trials require precise clinical management, complemented with detailed evaluation of safety and immune responses. Here, we review the pros and cons of available vaccine platforms and options to accelerate vaccine development towards the safe immunization of the world's population against SARS-CoV-2. Favorable vaccines, used in well-designed vaccination strategies, may be critical for limiting harm and promoting trust and a long-term return to normal public life and economy.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Rheumatologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Rheumatologie

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Rheumatology, Clinical Immunology and Allergology

UniBE Contributor:

Bachmann, Martin

Subjects:

600 Technology > 610 Medicine & health

ISSN:

2076-393X

Publisher:

MDPI

Language:

English

Submitter:

Lee-Anne Brand

Date Deposited:

11 Nov 2020 16:06

Last Modified:

06 Jan 2021 12:05

Publisher DOI:

10.3390/vaccines8030404

PubMed ID:

32707833

Uncontrolled Keywords:

COVID-19 SARS-CoV-2 immunity nucleic acid tests serology vaccination

BORIS DOI:

10.7892/boris.147935

URI:

https://boris.unibe.ch/id/eprint/147935

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