Cardiovascular and Pulmonary Challenges After Treatment of Childhood Cancer.

Visscher, Henk; Otth, Maria; Feijen, E A M Lieke; Nathan, Paul C; Kuehni, Claudia E (2020). Cardiovascular and Pulmonary Challenges After Treatment of Childhood Cancer. Pediatric clinics of North America, 67(6), pp. 1155-1170. Elsevier 10.1016/j.pcl.2020.07.007

	Text Visscher PediatrClinNorthAm 2020.pdf - Published Version Restricted to registered users only Available under License Publisher holds Copyright. Download (194kB) | Request a copy
Preview	Text Visscher_PediatrClinNorthAm_2020_AAM.pdf - Accepted Version Available under License Creative Commons: Attribution-Noncommercial-No Derivative Works (CC-BY-NC-ND). Download (438kB) | Preview

Childhood cancer survivors are at risk for developing cardiovascular disease and pulmonary disease related to cancer treatment. This might not become apparent until many years after treatment and varies from subclinical to life-threatening disease. Important causes are anthracyclines and radiotherapy involving heart, head, or neck for cardiovascular disease, and bleomycin, busulfan, nitrosoureas, radiation to the chest, and lung or chest surgery for pulmonary disease. Most effects are dose dependent, but genetic risk factors have been discovered. Treatment options are limited. Prevention and regular screening are crucial. Survivors should be encouraged to adopt a healthy lifestyle, and modifiable risk factors should be addressed.

Interest & Impact

Downloads

17 since deposited on 10 Nov 2020
13 in the past 12 months

Citations

5 Citations in Web of Science ®
6 Citations in Scopus

Search

in Google Scholar™

Services

Actions (login required)

Edit item

Actions (login required)

Edit item