Late Effects in Childhood Cancer Survivors: Early Studies, Survivor Cohorts, and Significant Contributions to the Field of Late Effects.

Norsker, Filippa Nyboe; Pedersen, Camilla; Armstrong, Gregory T; Robison, Leslie L; McBride, Mary L; Hawkins, Michael; Kuehni, Claudia E; de Vathaire, Florent; Berbis, Julie; Kremer, Leontien C; Haupt, Riccardo; Kenborg, Line; Winther, Jeanette Falck (2020). Late Effects in Childhood Cancer Survivors: Early Studies, Survivor Cohorts, and Significant Contributions to the Field of Late Effects. Pediatric clinics of North America, 67(6), pp. 1033-1049. Elsevier 10.1016/j.pcl.2020.07.002

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With improvement in cure of childhood cancer came the responsibility to investigate the long-term morbidity and mortality associated with the treatments accountable for this increase in survival. Several large cohorts of childhood cancer survivors have been established throughout Europe and North America to facilitate research on long-term complications of cancer treatment. The cohorts have made significant contributions to the understanding of early mortality, somatic late complications, and psychosocial outcomes among childhood cancer survivors, which has been translated into the design of new treatment protocols for pediatric cancers, with the goal to reduce the potential risk and severity of late effects.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine > Paediatric Haematology/Oncology
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM)

UniBE Contributor:

Kühni, Claudia

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

1557-8240

Publisher:

Elsevier

Language:

English

Submitter:

Anette van Dorland

Date Deposited:

10 Nov 2020 23:53

Last Modified:

05 Dec 2022 15:41

Publisher DOI:

10.1016/j.pcl.2020.07.002

PubMed ID:

33131533

Uncontrolled Keywords:

Cancer research Childhood cancer survivors Late effects Long-term complications Survivor cohorts

BORIS DOI:

10.7892/boris.148025

URI:

https://boris.unibe.ch/id/eprint/148025

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