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La Mura, Vincenzo; Villanueva, Candid; Abraldes, Juan G; Bosch, Jaime (2020). Reply. Hepatology, 72(4), pp. 1494-1495. Wiley 10.1002/hep.31253

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We thank Kumar and colleagues for their interest in our new algorithm for risk-stratification in candidates to secondary prophylaxis of variceal bleeding. In this algorithm, patients that bleed without other manifestations of hepatic decompensation are classified as low-risk without measuring the hepatic venous pressure gradient (HVPG). Using our new algorithm, a large number of invasive and costly HVPG measurements can be saved. More importantly, the number of high-risk patients who did not rebleed during follow-up (the "grey zone") decreased from 43% to 23%, demonstrating great accuracy in selecting high-risk patients.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie

UniBE Contributor:

Bosch, Jaime

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1527-3350

Publisher:

Wiley

Language:

English

Submitter:

Rahel Fuhrer

Date Deposited:

18 Dec 2020 15:51

Last Modified:

18 Dec 2020 15:51

Publisher DOI:

10.1002/hep.31253

PubMed ID:

32246502

BORIS DOI:

10.7892/boris.148189

URI:

https://boris.unibe.ch/id/eprint/148189

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