Patterns among Patients with Chronic Pruritus: A Retrospective Analysis of 170 Patients.

Lehmann, Mathias; Cazzaniga, Simone; Simon, Dagmar; Perruchoud, Delphine L.; Borradori, Luca; Rammlmair, Anna (2020). Patterns among Patients with Chronic Pruritus: A Retrospective Analysis of 170 Patients. Acta dermato-venereologica, 100(4), adv00068. Acta Dermato-Venereologica 10.2340/00015555-3405

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Chronic pruritus profoundly affects patients' quality of life. The objective of this retrospective cross-sectional study was to characterize patients with chronic pruritus and identify patterns, in order to delineate a better diagnostic approach. Both semantic connectivity map and classical analysis were applied, linking demographic, clinical, laboratory and histopathological data with clinical and aetiological categories of 170 patients with chronic pruritus (median age 72 years, 58.2% women). The semantic map showed clinical categories separated in different hubs associated with distinct patterns concerning sex, aetiology, laboratory findings, and pharmacological treatment. Diabetes, diagnosis of cancer and psychiatric comorbidities were linked with certain clinical categories. Skin eosinophilia was a common finding of chronic pruritus, on both diseased and non-diseased skin. High frequencies of patients with chronic pruritus taking anti-arrhythmics, beta-blockers and AT-II receptor antagonists were noticed among those with underlying systemic, neurological and psychiatric diseases. This study provides a complex analysis of chronic pruritus and thus basic principles for a clinical work-up.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology

Graduate School:

Graduate School for Cellular and Biomedical Sciences (GCB)

UniBE Contributor:

Lehmann, Mathias; Cazzaniga, Simone; Simon, Dagmar; Borradori, Luca and Rammlmair, Anna

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1651-2057

Publisher:

Acta Dermato-Venereologica

Language:

English

Submitter:

Sandra Nyffenegger

Date Deposited:

10 Dec 2020 17:47

Last Modified:

13 Dec 2020 02:51

Publisher DOI:

10.2340/00015555-3405

PubMed ID:

31950196

Uncontrolled Keywords:

classification eosino­philia semantic map chronic pruritus

BORIS DOI:

10.7892/boris.148328

URI:

https://boris.unibe.ch/id/eprint/148328

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