Azparren-Angulo, Maria; Royo, Felix; Gonzalez, Esperanza; Liebana, Marc; Brotons, Bruno; Berganza, Jesús; Goñi-de-Cerio, Felipe; Manicardi, Nicoló; Abad-Jordà, Laia; Gracia Sancho, Jorge; Falcon-Perez, Juan M (2021). Extracellular vesicles in hepatology: Physiological role, involvement in pathogenesis, and therapeutic opportunities. Pharmacology & therapeutics, 218, p. 107683. Elsevier 10.1016/j.pharmthera.2020.107683
|
Text
1-s2.0-S0163725820302138-main.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (1MB) | Preview |
Since the first descriptions of hepatocyte-released exosome-like vesicles in 2008, the number of publications describing Extracellular Vesicles (EVs) released by liver cells in the context of hepatic physiology and pathology has grown exponentially. This growing interest highlights both the importance that cell-to-cell communication has in the organization of multicellular organisms from a physiological point of view, as well as the opportunity that these circulating organelles offer in diagnostics and therapeutics. In the present review, we summarize systematically and comprehensively the myriad of works that appeared in the last decade and lighted the discussion about the best opportunities for using EVs in liver disease therapeutics.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Hepatologie 04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine |
UniBE Contributor: |
Gracia Sancho, Jorge Sergio |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0163-7258 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Thi Thao Anh Pham |
Date Deposited: |
09 Dec 2020 18:28 |
Last Modified: |
05 Dec 2022 15:42 |
Publisher DOI: |
10.1016/j.pharmthera.2020.107683 |
PubMed ID: |
32961265 |
Uncontrolled Keywords: |
Diagnostics EVs Exosomes Liver disease Microvesicles Therapeutics |
BORIS DOI: |
10.7892/boris.148515 |
URI: |
https://boris.unibe.ch/id/eprint/148515 |
Actions (login required)
 |
Edit item |