Sodium Hypochlorite as an Adjunct to Nonsurgical Treatment of Periodontitis: A Systematic Review.

Ramanauskaitè, Eglè; Machiulskiene, Vita; Eliezer, Meizi; Sculean, Anton (2020). Sodium Hypochlorite as an Adjunct to Nonsurgical Treatment of Periodontitis: A Systematic Review. Oral health & preventive dentistry, 18(1), pp. 881-887. Quintessenz Verlags-GmbH 10.3290/j.ohpd.a45405

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PURPOSE

To evaluate effects of the adjunctive subgingival application of sodium hypochlorite on clinical outcome following nonsurgical periodontal treatment.

MATERIALS AND METHODS

A search protocol was developed to answer the following focused question: 'in patients with periodontitis, does adjunctive subgingival application of sodium hypochlorite have additional clinical benefits compared to subgingival debridement alone?' Randomised controlled clinical trials (RCTs) published up to January 30, 2020, with at least 6 months of follow-up, in which sodium hypochlorite was used as an adjunct in nonsurgical periodontitis treatment were included. The search was limited to the English language.

RESULTS

Out of 355 studies retrieved, the search resulted in two publications that fulfilled the inclusion criteria. The adjunctive application of sodium hypochlorite did not provide additional beneficial effect in terms of changes in the evaluated clinical outcomes (i.e. probing depth values [PDs], clinical attachment level gain [CAL] and bleeding on probing [BOP]) when compared to mechanical instrumentation alone over the 12-month investigation period (p > 0.05).

CONCLUSION

The available data have failed to show any additional clinical benefit following the use of sodium hypochlorite in conjunction with nonsurgical periodontal therapy.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > School of Dental Medicine > Department of Periodontology
04 Faculty of Medicine > School of Dental Medicine > School of Dental Medicine, Periodontics Research

UniBE Contributor:

Ramanauskaitè, Eglè; Eliezer-Shatz, Meizi and Sculean, Anton

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1602-1622

Publisher:

Quintessenz Verlags-GmbH

Language:

English

Submitter:

Doris Burri

Date Deposited:

01 Dec 2020 10:42

Last Modified:

01 Dec 2020 10:42

Publisher DOI:

10.3290/j.ohpd.a45405

PubMed ID:

33215480

Uncontrolled Keywords:

periodontitis review therapy treatment

BORIS DOI:

10.7892/boris.148681

URI:

https://boris.unibe.ch/id/eprint/148681

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