Age dependency of body mass index distribution in childhood and adolescent inpatients with anorexia nervosa with a focus on DSM-5 and ICD-11 weight criteria and severity specifiers

Engelhardt, Christian; Föcker, Manuel; Bühren, Katharina; Dahmen, Brigitte; Becker, Katja; Weber, Linda; Correll, Christoph U.; Egberts, Karin Maria; Ehrlich, Stefan; Roessner, Veit; Fleischhaker, Christian; von Gontard, Alexander; Hahn, Freia; Jenetzky, Ekkehart; Kaess, Michael; Legenbauer, Tanja; Renner, Tobias J.; Schulze, Ulrike M. E.; Sinzig, Judith; Wessing, Ida; ... (2020). Age dependency of body mass index distribution in childhood and adolescent inpatients with anorexia nervosa with a focus on DSM-5 and ICD-11 weight criteria and severity specifiers (In Press). European child & adolescent psychiatry Springer 10.1007/s00787-020-01595-4

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Both DSM-5 and ICD-11 have provided weight cut-offs and severity specifiers for the diagnosis of anorexia nervosa (AN) in childhood, adolescence and adulthood. The aims of the current study focusing on inpatients aged < 19 years were to assess (1) the relationship between age and body mass index (BMI; kg/m2), BMI-centiles, BMI-standard deviation scores (BMI-SDS) and body height-SDS at referral, (2) the percentages of patients fulfilling the DSM-5 and ICD-11 weight criteria and severity categories for AN, and (3) the validity of the AN severity specifiers via analysis of both weight related data at discharge and inpatient treatment duration. The German Registry for Anorexia Nervosa encompassed complete data sets for 469 female patients (mean age = 15.2 years; range 8.9-18.9 years) with a diagnosis of AN (n = 404) or atypical AN (n = 65), who were ascertained at 16 German child and adolescent psychiatric hospitals. BMI at referral increased up to age 15 to subsequently plateau. Approximately one tenth of all patients with AN had a BMI above the fifth centile. The ICD-11 specifier based on a BMI-centile of 0.3 for childhood and adolescent AN entailed two equally sized groups of patients. Discharge data revealed limited validity of the specifiers. Height-SDS was not correlated with age thus stunting had no impact on our data. We corroborate the evidence to use the tenth instead of the fifth BMI-centile as the weight criterion in children and adolescents. Weight criteria should not entail major diagnostic shifts during the transition from adolescence to adulthood. The severity specifiers based on BMI or BMI-centiles do not seem to have substantial clinical validity.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > University Psychiatric Services > University Hospital of Child and Adolescent Psychiatry and Psychotherapy
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Child and Adolescent Psychiatry and Psychotherapy > Research Division

UniBE Contributor:

Kaess, Michael

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1018-8827

Publisher:

Springer

Language:

English

Submitter:

Chantal Michel

Date Deposited:

24 Dec 2020 10:15

Last Modified:

25 Dec 2020 01:34

Publisher DOI:

10.1007/s00787-020-01595-4

PubMed ID:

32666204

BORIS DOI:

10.48350/148965

URI:

https://boris.unibe.ch/id/eprint/148965

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