Ultra high dose rate Synchrotron Microbeam Radiation Therapy. Preclinical evidence in view of a clinical transfer.

Eling, Laura; Bouchet, Audrey Michele; Nemoz, Christian; Djonov, Valentin; Balosso, Jacques; Laissue, Jean; Bräuer-Krisch, Elke; Adam, Jean Francois; Serduc, Raphael (2019). Ultra high dose rate Synchrotron Microbeam Radiation Therapy. Preclinical evidence in view of a clinical transfer. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 139, pp. 56-61. Elsevier Scientific Publ. Ireland 10.1016/j.radonc.2019.06.030

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This paper reviews the current state of the art of an emerging form of radiosurgery dedicated to brain tumour treatment and which operates at very high dose rate (kGy·s-1). Microbeam Radiation Therapy uses synchrotron-generated X-rays which triggered normal tissue sparing partially mediated by FLASH effect.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Anatomy > Topographical and Clinical Anatomy

UniBE Contributor:

Bouchet, Audrey Michele; Djonov, Valentin Georgiev and Laissue, Jean

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1879-0887

Publisher:

Elsevier Scientific Publ. Ireland

Language:

English

Submitter:

David Christian Haberthür

Date Deposited:

30 Dec 2020 09:17

Last Modified:

30 Dec 2020 09:27

Publisher DOI:

10.1016/j.radonc.2019.06.030

PubMed ID:

31307824

Uncontrolled Keywords:

Brain tumours responses High dose rate Normal tissue sparing Synchrotron Microbeam Radiation Therapy

BORIS DOI:

10.48350/149213

URI:

https://boris.unibe.ch/id/eprint/149213

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