Therapies in Inflammatory Bowel Disease Patients with Extraintestinal Manifestations.

Juillerat, Pascal; Manz, Michael; Sauter, Bernhard; Zeitz, Jonas; Vavricka, Stephan R. (2020). Therapies in Inflammatory Bowel Disease Patients with Extraintestinal Manifestations. Digestion, 101(S1), pp. 83-97. Karger 10.1159/000502816

[img] Text
502816.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (412kB) | Request a copy

Extraintestinal manifestations (EIM) have become an important source of morbidity and disability as well as an identified risk factor for an unfavorably course of disease in inflammatory bowel diseases (IBD). Therefore, efforts have been put into a more global and interdisciplinary management of IBD patients in collaboration with rheumatologists, dermatologists, and ophthalmologists. A real therapeutic success has also been obtained with a more "systemic" IBD treatment associated with the development of monoclonal antibodies against TNF alpha and biological agents derived from the treatment of rheumatological disease (also called biological Disease-Modifying Antirheumatic Drugs). The prevalence of these EIM remains too low to undergo randomized controlled trials with this specific focus and therefore the evidence relies on case series and experts' opinions, which lowers the level of evidence. After a careful review of the most recent literature, this paper aims to update the reader on the latest therapeutic management of IBD patients with EIM.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Gastroenterology
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Gastroenterologie / Mukosale Immunologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Gastroenterologie / Mukosale Immunologie

UniBE Contributor:

Juillerat, Pascal

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0012-2823

Publisher:

Karger

Language:

English

Submitter:

Rahel Fuhrer

Date Deposited:

22 Dec 2020 11:40

Last Modified:

22 Dec 2020 11:40

Publisher DOI:

10.1159/000502816

PubMed ID:

32066137

Uncontrolled Keywords:

Ankylosing spondyloarthritis Crohn’s disease Extraintestinal manifestations Inflammatory bowel disease Infliximab Ulcerative colitis

BORIS DOI:

10.7892/boris.149245

URI:

https://boris.unibe.ch/id/eprint/149245

Actions (login required)

Edit item Edit item
Provide Feedback