A strategic Ser/Cys exchange in the catalytic triad unlocks an acyltransferase-mediated synthesis of thioesters and tertiary amides

Contente, Martina L.; Roura Padrosa, David; Molinari, Francesco; Paradisi, Francesca (2020). A strategic Ser/Cys exchange in the catalytic triad unlocks an acyltransferase-mediated synthesis of thioesters and tertiary amides. Nature catalysis, 3(12), pp. 1020-1026. Nature Publishing Group 10.1038/s41929-020-00539-0

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Item Type:

Journal Article (Original Article)

Division/Institute:

08 Faculty of Science > Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP)

UniBE Contributor:

Contente, Martina Letizia; Roura Padrosa, David and Paradisi, Francesca

Subjects:

500 Science > 570 Life sciences; biology
500 Science > 540 Chemistry

ISSN:

2520-1158

Publisher:

Nature Publishing Group

Funders:

[UNSPECIFIED] H2020-MSCA-IF-2018 Project ID 753878 ; [UNSPECIFIED] Swiss National Science Foundation 200021_192274

Projects:

[UNSPECIFIED] Artificial Enzymatic Factories

Language:

English

Submitter:

Francesca Paradisi

Date Deposited:

20 Jan 2021 08:55

Last Modified:

01 Jun 2021 02:30

Publisher DOI:

10.1038/s41929-020-00539-0

BORIS DOI:

10.48350/149266

URI:

https://boris.unibe.ch/id/eprint/149266

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