Uter, Wolfgang; Bauer, Andrea; Belloni Fortina, Anna; Bircher, Andreas J; Brans, Richard; Buhl, Timo; Cooper, Susan M; Czarnecka-Operacz, Magdalena; Dickel, Heinrich; Dugonik, Aleksandra; Geier, Johannes; Giménez-Arnau, Ana M; Gonçalo, Margarida; Johansen, Jeanne D; Johnston, Graham A; Mahler, Vera; Rustemeyer, Thomas; Sanchez-Perez, Javier; Schuttelaar, Marie L A; Simon, Dagmar; ... (2021). Patch test results with the European baseline series and additions thereof in the ESSCA network, 2015-2018. Contact dermatitis, 84(2), pp. 109-120. Wiley-Blackwell 10.1111/cod.13704
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BACKGROUND
Clinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the importance of contact allergens (haptens) assembled in a baseline series.
OBJECTIVES
To present current results from the European Surveillance System on Contact Allergies, including 13 countries represented by 1 to 11 departments.
METHODS
Anonymized or pseudonymized patch test and clinical data from various data capture systems used locally or nationally as transferred to the Erlangen data centre were pooled and descriptively analysed after quality control.
RESULTS
In the 4 years (2015-2018), data from 51 914 patients patch tested with the European baseline series (EBS) of contact allergens were analysed. Contact allergy to nickel was most frequent (17.6% positive), followed by contact allergy to fragrance mix I (6.9%), methylisothiazolinone (MI; 6.2%), and Myroxylon pereirae resin (balsam of Peru; 5.8%).
CONCLUSIONS
While the prevalence of MI contact allergy decreased substantially following regulatory intervention, the persistently high levels of allergy to metals, fragrances, other preservatives, and rubber chemicals point to problems needing further research and, potentially, preventive efforts. Results with national additions to the baseline series provide important information on substances possibly to be considered for inclusion in the EBS.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology |
UniBE Contributor: |
Simon, Dagmar |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0105-1873 |
Publisher: |
Wiley-Blackwell |
Language: |
English |
Submitter: |
Andrea Studer-Gauch |
Date Deposited: |
04 Jan 2021 14:46 |
Last Modified: |
05 Dec 2022 15:42 |
Publisher DOI: |
10.1111/cod.13704 |
PubMed ID: |
32945543 |
Uncontrolled Keywords: |
RRID:SCR_001905 clinical epidemiology contact allergy patch testing surveillance |
BORIS DOI: |
10.48350/149451 |
URI: |
https://boris.unibe.ch/id/eprint/149451 |
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