Patch test results with the European baseline series and additions thereof in the ESSCA network, 2015-2018.

Uter, Wolfgang; Bauer, Andrea; Belloni Fortina, Anna; Bircher, Andreas J; Brans, Richard; Buhl, Timo; Cooper, Susan M; Czarnecka-Operacz, Magdalena; Dickel, Heinrich; Dugonik, Aleksandra; Geier, Johannes; Giménez-Arnau, Ana M; Gonçalo, Margarida; Johansen, Jeanne D; Johnston, Graham A; Mahler, Vera; Rustemeyer, Thomas; Sanchez-Perez, Javier; Schuttelaar, Marie L A; Simon, Dagmar; ... (2021). Patch test results with the European baseline series and additions thereof in the ESSCA network, 2015-2018. Contact dermatitis, 84(2), pp. 109-120. Wiley-Blackwell 10.1111/cod.13704

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BACKGROUND

Clinical surveillance of the prevalence of contact allergy in consecutively patch tested patients is a proven instrument to continually assess the importance of contact allergens (haptens) assembled in a baseline series.

OBJECTIVES

To present current results from the European Surveillance System on Contact Allergies, including 13 countries represented by 1 to 11 departments.

METHODS

Anonymized or pseudonymized patch test and clinical data from various data capture systems used locally or nationally as transferred to the Erlangen data centre were pooled and descriptively analysed after quality control.

RESULTS

In the 4 years (2015-2018), data from 51 914 patients patch tested with the European baseline series (EBS) of contact allergens were analysed. Contact allergy to nickel was most frequent (17.6% positive), followed by contact allergy to fragrance mix I (6.9%), methylisothiazolinone (MI; 6.2%), and Myroxylon pereirae resin (balsam of Peru; 5.8%).

CONCLUSIONS

While the prevalence of MI contact allergy decreased substantially following regulatory intervention, the persistently high levels of allergy to metals, fragrances, other preservatives, and rubber chemicals point to problems needing further research and, potentially, preventive efforts. Results with national additions to the baseline series provide important information on substances possibly to be considered for inclusion in the EBS.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology

UniBE Contributor:

Simon, Dagmar

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0105-1873

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Sandra Nyffenegger

Date Deposited:

04 Jan 2021 14:46

Last Modified:

10 Mar 2021 21:28

Publisher DOI:

10.1111/cod.13704

PubMed ID:

32945543

Uncontrolled Keywords:

RRID:SCR_001905 clinical epidemiology contact allergy patch testing surveillance

BORIS DOI:

10.48350/149451

URI:

https://boris.unibe.ch/id/eprint/149451

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