Secondary stroke prevention: patent foramen ovale, aortic plaque, and carotid stenosis

Meier, Bernhard; Frank, Benedikt; Wahl, Andreas; Diener, Hans C (2012). Secondary stroke prevention: patent foramen ovale, aortic plaque, and carotid stenosis. European Heart Journal, 33(6), 705-13, 713a, 713b. Oxford: Oxford University Press 10.1093/eurheartj/ehr443

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Stroke is the most debilitating cardiovascular event. It has a variety of causes that may be present simultaneously. In young or otherwise healthy people, the search for a patent foramen ovale (PFO) has become standard. In stroke of the elderly, atherosclerosis and atrial fibrillation are in the foreground but the PFO should not be ignored. The risk of a PFO-related stroke over time is controversial and so is its prevention by device closure. The association of proximal aortic plaques in arteries subtending the brain and stroke is considered strong, ignoring that it is as putative as that of the PFO. Statins can prevent progression of such plaques. Antiplatelet agents in asymptomatic and surgical endarterectomy in symptomatic patients or highly ulcerated lesions are the treatment of choice. Stenting with protection devices was shown competitive in selected patients.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology

UniBE Contributor:

Meier, Bernhard and Wahl, Andreas

ISSN:

0195-668X

Publisher:

Oxford University Press

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:37

Last Modified:

26 Oct 2019 06:22

Publisher DOI:

10.1093/eurheartj/ehr443

PubMed ID:

22422912

Web of Science ID:

000302022600013

BORIS DOI:

10.7892/boris.14971

URI:

https://boris.unibe.ch/id/eprint/14971 (FactScience: 222118)

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