Stute, P.; Stadler, A; Heufelder, A (2020). The impact of menopausal hormone therapy on overall mortality - a comprehensive review. Climacteric, 23(5), pp. 447-459. Informa Healthcare 10.1080/13697137.2020.1767568
Full text not available from this repository.Menopausal hormone therapy (MHT) is indicated for menopausal symptom relief. However, MHT has also been shown to be beneficial for prevention of long-term estrogen deficiency sequelae including mortality. Based on a comprehensive literature review on MHT and mortality, the authors' recommendations are as follows: in postmenopausal women, MHT appears to confer a (significant) reduction in overall mortality; the benefit especially applies to women who initiate long-term MHT early after menopause; in women with prevalent cardiovascular risk factors (except for diabetes mellitus, where results are mixed), the benefit of MHT on overall mortality is even more pronounced; and, however, study results are difficult to compare due to heterogeneous study designs.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Gynaecology |
UniBE Contributor: |
Stute, Petra |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
1369-7137 |
Publisher: |
Informa Healthcare |
Language: |
English |
Submitter: |
Monika Zehr |
Date Deposited: |
13 Jan 2021 10:03 |
Last Modified: |
05 Dec 2022 15:43 |
Publisher DOI: |
10.1080/13697137.2020.1767568 |
PubMed ID: |
32552066 |
Uncontrolled Keywords: |
Menopausal hormone therapy age at initiation overall mortality review treatment duration |
URI: |
https://boris.unibe.ch/id/eprint/150156 |
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